TY  - JOUR
PY  - 2022//
TI  - First death involving 4-fluoroethylphenidate (4F-EPH): case report, user experiences, and review of the related literature
JO  - Academic forensic pathology
A1  - Corkery, John Martin
A1  - Schifano, Fabrizio
SP  - 149
EP  - 166
VL  - 12
IS  - 4
N2  - BACKGROUND: 4-Fluoroethylphenidate (4F-EPH) is a psychoactive substance, sold primarily over the Internet as a 'research chemical'. Recreational and 'functional' use of this drug has been reported by online user fora. Scientifically-based data on the pharmacological, physiological, psychopharmacological, toxicological, and epidemiological characteristics of this molecule is non-existent. The aim of this paper is to remedy this situation.   METHODS: Recent literature (including 'grey') was searched to update what is known about 4F-EPH, especially its toxicity. This was supplemented by netnographic examinations of internet sites.   RESULTS: The resultant information is presented, including details of the first reported death involving 4F-EPH use in 2016. There are no international controls imposed on 4F-EPH. However, it has been made a controlled drug in several European countries, including the United Kingdom since 31 May 2017, as well as Canada.   CONCLUSIONS: It is vital that any other cases, including non-fatal overdoses, are documented so that a firmer scientific evidence-base can be established for this molecule. This will then help inform clinical practice.<p />  <p>Language: en</p>
LA  - en
SN  - 1925-3621
UR  - http://dx.doi.org/10.1177/19253621221142480
ID  - ref1
ER  -