TY  - JOUR
PY  - 2024//
TI  - Understanding comorbidity between non-suicidal self-injury and depressive symptoms in a clinical sample of adolescents: a network analysis
JO  - Neuropsychiatric disease and treatment
A1  - Niu, Shan
A1  - Yin, Xiaoxiao
A1  - Pan, Bing
A1  - Chen, Haotian
A1  - Dai, Chunxiao
A1  - Tong, Chunnan
A1  - Chen, Fang
A1  - Feng, Xiuqin
SP  - 1
EP  - 17
VL  - 20
IS  - 
N2  - BACKGROUND: Non-suicidal self-injury (NSSI) and depression often co-occur among adolescents with more severe clinical symptoms. This study examined the network structures of NSSI and depressive symptoms in adolescents. <br><br>METHODS: Participants were recruited in the psychiatric outpatient clinics of three tertiary hospitals between April 10 and July 10, 2023. All participants been already found with self-injury behaviors in outpatient when enrolled. NSSI diagnostic criteria and Patient Health Questionnaire-9 (PHQ-9) were utilized to collect NSSI and depressive symptoms separately. We performed a network analysis to visualize the correlation between each symptom and to identify core and bridging symptoms in comorbidities. <br><br>RESULTS: A total of 248 patients were enrolled in the study, with a mean age of 15.48 (SD = 1.62). Based on the PHQ-9 scores and grades, our results showed that the incidence of depression in adolescents with non-suicidal self-injury behavior was relatively high (N=235, 94.76%), with the majority having severe depression. The network analysis revealed that nodes D-6 "feeling bad, failing or letting yourself or your family down", D-1 "little interest or pleasure" and D-4 "feeling tired" were the most vital and most central symptoms. The most crucial bridging symptom is the node NSSI-8 "frequent thinking about self-injury", which connects the NSSI to the depression comorbid network. <br><br>CONCLUSION: This study offers a significant symptom-level conceptualization of the association between NSSI and depressive symptoms in a clinical sample of adolescents, which not only enhances our understanding of the comorbid but also identifies potential treatment targets to prevent and treat comorbidity between adolescent NSSI and depression.<p />  <p>Language: en</p>
LA  - en
SN  - 1176-6328
UR  - http://dx.doi.org/10.2147/NDT.S443454
ID  - ref1
ER  -