TY - JOUR PY - 2024// TI - Cannabis-induced psychotic disorder with onset during withdrawal: a brief report of emerging evidence JO - Acta neuropsychiatrica A1 - Cohen, Johan A1 - Petitjean, Hugues A1 - Blasco, M. Belen A1 - Mizrahi, Romina SP - ePub EP - ePub VL - ePub IS - ePub N2 - OBJECTIVES: The link between cannabis use and psychotic symptoms or disorders is well known. However, the relation between cannabis withdrawal and psychotic symptoms is less studied.

METHODS: To our knowledge, this is the first publication of an observational systematic report of cannabis-induced psychotic disorder with onset during withdrawal. Here, we review patients presenting to a major emergency room in Montreal between January 2020 and September 2023 in a context of psychotic symptoms following cannabis cessation.

RESULTS: 7 male and 1 female patients presented at the peak of cannabis withdrawal with acute psychotic symptoms, representing less than 1% of all emergency service admissions.

CONCLUSIONS: We discuss current knowledge regarding the endocannabinoid system and dopamine homeostasis to formulate hypothesis regarding these observations.

Language: en

LA - en SN - 0924-2708 UR - http://dx.doi.org/10.1017/neu.2023.60 ID - ref1 ER -