TY  - JOUR
PY  - 2024//
TI  - Acute alcohol intoxication-related metabolic and biochemical disturbances in adolescents: a matched case-control study
JO  - Clinical pediatrics
A1  - Hanalıoğlu, Damla
A1  - Ozkocer, Cansu
A1  - Can Ozalp, Esra
A1  - Dikmen, Zeliha Gunnur
A1  - Pinar, Asli
A1  - Teksam, Ozlem
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - We aimed to investigate clinical and laboratory characteristics of acute alcohol intoxication (AAI) in adolescents who presented to the pediatric emergency department (ED) at a tertiary referral center from 2006 to 2019. All consecutive adolescents with AAI (n = 335) and their sex- and age-matched control subjects (n = 335) with undetectable ethanol levels were included in this case-matched study. Mean serum ethanol level was 156.4 ± 58.4 (range: 50.8-341.2) mg/dL in the acute alcohol intoxication (AAI) group. Glasgow coma scores were lower in AAI group (14 [14-15] vs 15 [15-15], P <.001). Acidosis (16.3%), hyperlactatemia (60.9%), hypoglycemia (1.7%), hypernatremia (2.2%), hypokalemia (12.3%), hyperchloremia (20.4%), hypocalcemia (13.9%), hypermagnesemia (9.7%), and hyperalbuminemia (10.4%) were significantly more common in the AAI group than the control group. Blood pH, lactate, Na+, K+, Ca++, Mg++, albumin, blood urea nitrogen (BUN), and uric acid levels were correlated with serum ethanol levels. This study shows that AAI frequently leads to mild to moderate metabolic/biochemical derangements in adolescents.<p />  <p>Language: en</p>
LA  - en
SN  - 0009-9228
UR  - http://dx.doi.org/10.1177/00099228231225164
ID  - ref1
ER  -