TY  - JOUR
PY  - 2024//
TI  - Cannabis-related disorders and toxic effects
JO  - New England journal of medicine
A1  - Hassouneh, Ala'
A1  - Tambyraja, Andrew L.
SP  - e867
EP  - e867
VL  - 390
IS  - 9
N2  - To the Editor: The review by Gorelick (Dec. 14 issue)1 regarding cannabis-related disorders highlights many of the toxic sequelae associated with the misuse of this substance. In addition, cannabis use may cause a distinct inflammatory arteritis affecting the small and medium-sized peripheral arteries in a clinical pattern similar to that seen in tobacco-associated thromboangiitis obliterans.2 More commonly, cannabis use is associated with an increased risk of premature atherosclerotic peripheral vascular disease.3 Distinguishing between these two cannabis-related arteriopathies is clinically challenging, and considerable overlap is most likely. The proposed mechanisms of cannabis-related arteriopathy are underpinned by arteritis, vasospasm, and platelet aggregation. . . .<p />  <p>Language: en</p>
LA  - en
SN  - 0028-4793
UR  - http://dx.doi.org/10.1056/NEJMc2400805
ID  - ref1
ER  -