TY  - JOUR
PY  - 2024//
TI  - Does adjunctive hemoadsorption provide benefit in the management of ischemia-reperfusion syndrome following near-drowning? A case report
JO  - Frontiers in medicine
A1  - Kovacevic, Pedja
A1  - Dragic, Sasa
A1  - Jandric, Milka
A1  - Momcicevic, Danica
A1  - Malesevic, Vedrana
A1  - Kovacevic, Tijana
A1  - Matejic-Spasic, Marijana
A1  - Knezevic, Tanja
A1  - Zlojutro, Biljana
SP  - e1341156
EP  - e1341156
VL  - 11
IS  - 
N2  - Drowning remains a significant global health concern, claiming over 300,000 lives annually, with a disproportionate impact on young individuals in low-and middle-income countries. Conventional mechanical ventilation, while common, falls short in addressing the hypoxemia and hypercapnia often observed in severe near-drowning cases. Veno-venous extracorporeal membrane oxygenation (vvECMO) emerges as a critical intervention for cardiopulmonary failure post-drowning. This case report delves into the pivotal role of ischemia-reperfusion injury (IRI) in a near-drowning-related pathology. Following the initial insult, reoxygenation exacerbates the inflammatory cascade, resulting in a surge of pro-inflammatory mediators. In this context, CytoSorb(®), a hemoadsorption cartridge, demonstrates promise by effectively removing these mediators from circulation. This report outlines its application in a critically ill adolescent patient who experienced near-drowning, presenting a compelling case for CytoSorb as an adjunctive therapy in managing IRI-induced hyperinflammation.<p />  <p>Language: en</p>
LA  - en
SN  - 2296-858X
UR  - http://dx.doi.org/10.3389/fmed.2024.1341156
ID  - ref1
ER  -