TY - JOUR PY - 2000// TI - Pulse steroid therapy in adult respiratory distress syndrome following petroleum naphtha ingestion JO - Journal of toxicology - clinical toxicology A1 - Kamijo, Y. A1 - Soma, K. A1 - Asari, Y. A1 - Ohwada, T. SP - 59 EP - 62 VL - 38 IS - 1 N2 - A suicide attempt by a 23-year-old woman involved ingestion of 1000 mL of petroleum naphtha. Early chemical pneumonitis was complicated by life-threatening, diffuse interstitial lung consolidation with pneumatoceles. Pulse steroid therapy beginning on day 17 was associated with remarkable resolution of interstitial consolidation, although an enlarging secondarily infected pneumatocele ruptured to produce a bronchopleural fistula. Thoracic surgery and antibiotic therapy resulted in improvement of the patient's respiratory condition, and she was discharged with no residual respiratory symptoms. High-dose corticosteroid therapy appears to be a useful addition to aggressive supportive treatment in late adult respiratory distress syndrome following hydrocarbon ingestion.
Language: en
LA - en SN - 0731-3810 UR - http://dx.doi.org/10.1081/clt-100100918 ID - ref1 ER -