TY  - JOUR
PY  - 2000//
TI  - Clinical and epidemiological study of patients hospitalized for major depressive episode
JO  - Annales medico-psychologiques
A1  - Montagnon, F.
A1  - Saïd, S.
A1  - Payan, C.
A1  - Corruble, E.
A1  - Taleb, M.
A1  - Rouillon, F.
SP  - 11
EP  - 20
VL  - 158
IS  - 1
N2  - We conducted a prospective study in hospitalized patients in order to evaluate the prevalence and the clinical characteristics of patients resistant to antidepressant treatment. 151 patients, fulfilling DSM-III-R criteria for major depressive episode, were included in the study; sex ratio was two women for one man and mean age was 44 years. 34% had no previous major depressive episode, 58% had melancholic features and 34% had attempted suicide. Comorbidity was high: 57%, 51% and 54% had another current diagnoses on axis I, II and III respectively. 30% were not previously treated with antidepressant. 27% were considered as resistant to antidepressant treatment: these patients were more frequently female, had a higher education level and a more severe disease with longer duration of depressive episodes, more frequent psychiatric care, high frequency of melancholic features, fewer psychosocial stress and increased TSH compared with non-resistant patients.<p /> <p>Language: en</p>
LA  - en
SN  - 0003-4487
UR  - http://dx.doi.org/
ID  - ref1
ER  -