TY - JOUR PY - 2002// TI - Down syndrome and major depressive disorder: A review JO - Mental Health Aspects of Developmental Disabilities A1 - Khan, S. A1 - Osinowo, T. A1 - Pary, R.J. SP - 46 EP - 52 VL - 5 IS - 2 N2 - The high prevalence of psychiatric disorders in individuals with mental retardation is fairly well established. Individuals with Down syndrome had been conceived in the past as happy and cheerful people and were thought not to suffer from Major Depressive Disorder. There is relatively limited data on the issue of Major Depressive Disorder and Down syndrome in the literature. However there is a growing body of evidence that individuals with Down syndrome do indeed suffer from Major Depressive Disorder. There is no neurobiological basis to suggest that Down syndrome and Major Depressive Disorder may be mutually exclusive. In this paper, we will review the current literature on Major Depressive Disorder in Individuals with Down syndrome and present updates on treatment.

Language: en

LA - en SN - 1057-3291 UR - http://dx.doi.org/ ID - ref1 ER -