TY  - JOUR
PY  - 2023//
TI  - Refractory cardiogenic shock caused by zinc phosphide toxicity
JO  - Proceedings: Baylor University Medical Center
A1  - Mittal, Nitish
A1  - Elmassry, Mohamed
A1  - Abohelwa, Mostafa
SP  - 224
EP  - 225
VL  - 36
IS  - 2
N2  - Zinc phosphide toxicity is a rare entity that presents most frequently among farmers in developing countries who use it as a rodenticide. The phosphine gas released after the ingestion inhibits cytochrome c oxidase, disrupting the mitochondrial physiology and oxidative phosphorylation and causing myocardial stunning. Here we present a case of a 20-year-old man who attempted suicide with zinc phosphide toxicity. Initially, he was hemodynamically stable with a normal ejection fraction; however, in a few hours, he deteriorated quickly and became hemodynamically unstable, with rapid deterioration of his ejection fraction to 20%. He was started on norepinephrine and then dobutamine; however, he had cardiac arrest from refractory cardiogenic shock despite resuscitative measures.<p />  <p>Language: en</p>
LA  - en
SN  - 0899-8280
UR  - http://dx.doi.org/10.1080/08998280.2022.2136920
ID  - ref1
ER  -