TY - JOUR PY - 2023// TI - Anhedonia and suicidal ideation in young people with early psychosis: further findings from the 2-year follow-up of the ReARMS program JO - Psychiatry research A1 - Poletti, Michele A1 - Pelizza, Lorenzo A1 - Loas, Gwenolé A1 - Azzali, Silvia A1 - Paterlini, Federica A1 - Garlassi, Sara A1 - Scazza, Ilaria A1 - Chiri, Luigi Rocco A1 - Pupo, Simona A1 - Raballo, Andrea SP - e115177 EP - e115177 VL - 323 IS - N2 - Hedonic deficits have been extensively studied in schizophrenia, but little is known about their association with suicidal ideation in early psychosis. The aim of this research was to examine the relationship between anhedonia and suicidal thoughts across a 2-year follow-up period in people with First Episode Psychosis (FEP) and at Ultra High Risk (UHR) of psychosis. Ninty-six UHR and 146 FEP, aged 13-35 years, completed the Comprehensive Assessment of At-Risk Mental States (CAARMS) and the Beck Depression Inventory-II (BDI-II). The BDI-II "Anhedonia" subscale score to assess anhedonia and the CAARMS "Depression" item 7.2 subscore to measure depression were used across the 2 years of follow-up. Hierarchical regression analyses were performed. No difference in anhedonia scores between FEP and UHR individuals was found. In the FEP group, a significant enduring association between anhedonia and suicidal ideation was found at baseline and across the follow-up, independent of clinical depression. In the UHR subgroup, the enduring relationship between anhedonia and suicidal thoughts were not completely independent from depression severity. Anhedonia is relevant in predicting suicidal ideation in early psychosis. Specific pharmacological and/or psychosocial interventions on anhedonia within specialized EIP program could reduce suicide risk overtime.
Language: en
LA - en SN - 0165-1781 UR - http://dx.doi.org/10.1016/j.psychres.2023.115177 ID - ref1 ER -