TY  - JOUR
PY  - 1999//
TI  - Axis I comorbidity in bipolar disorder with psychotic features
JO  - British journal of psychiatry
A1  - Pini, S.
A1  - Dell'Osso, L.
A1  - Mastrocinque, C.
A1  - Marcacci, G.
A1  - Papasogli, A.
A1  - Vignoli, S.
A1  - Pallanti, S.
A1  - Cassano, G.
SP  - 467
EP  - 471
VL  - 175
IS  - 
N2  - BACKGROUND: Axis I comorbidities are prevalent among patients with severe bipolar disorder but the clinical and psychopathological implications are not clear. AIMS: To investigate characteristics of four groups of patients categorised as follows: substance abuse only (group 1), substance abuse associated with other Axis I disorders (group 2), non-substance-abuse Axis I comorbidity (group 3), no psychiatric comorbidity (group 4). <br><br>METHOD: Consecutive patients with bipolar disorder with psychotic features (n = 125) were assessed using the Structured Clinical Interview for DSM-III-R--patient version, and several psychopathological scales. <br><br>RESULTS: By comparison with group 4, group 1 had a higher risk of having mood-incongruent delusions, group 2 had an earlier age at onset of mood disorder, a more frequent onset with a mixed state and a higher risk of suicide, and group 3 had more severe anxiety and a better awareness of illness. <br><br>CONCLUSIONS: Substance abuse, non-substance-abuse Axis I comorbidity and their reciprocal association are associated with different characteristics of bipolar disorder.<p /> <p>Language: en</p>
LA  - en
SN  - 0007-1250
UR  - http://dx.doi.org/10.1192/bjp.175.5.467
ID  - ref1
ER  -