TY - JOUR PY - 2003// TI - Donepezil in the treatment of mild to moderate Alzheimer's disease: Report of a Belgian multicenter study JO - Acta neurologica Belgica A1 - Santens, P. A1 - Ventura, M. SP - 159 EP - 163 VL - 103 IS - 3 N2 - In this report the results of a Belgian multicenter 24-week open-label study with donepezil in the treatment of mild to moderate Alzheimer's disease are described. Efficacy and safety were evaluated in a sample of 200 patients recruited in 25 Belgian centers. No significant changes could be found in cognition and behaviour over this 6-month period. Changes in daily functioning were small. Safety data were comparable to those reported in international trials. These results suggest that the findings of more robust double-blind, placebo-controlled studies can be confirmed in real life situations.

Language: en

LA - en SN - 0300-9009 UR - http://dx.doi.org/ ID - ref1 ER -