TY  - JOUR
PY  - 2005//
TI  - Cholesterol and suicide, coincidence or reality? A current state
JO  - Annales medico-psychologiques
A1  - Guillem, E.
A1  - Bouchez-Arbabzadeh, S.
A1  - Lépine, J.-p.
SP  - 577
EP  - 582
VL  - 163
IS  - 7
N2  - Several population-based and epidemiological studies showed an association between low levels of serum cholesterol and suicide. Controlled clinical studies have shown a statistically significant relation between low levels of serum cholesterol and risk of suicide. Major depression appears to be significantly associated with low serum cholesterol levels. In addition, personality traits such as impulsive behaviour characterized by hetero-aggressive acts and physical violence which are involved in suicide have been shown to be associated with low serum cholesterol. Major findings in the neurobiology of suicide, and more specifically in studies of violent suicide, have also implicated low levels of serotonin. However, the biological studies in humans concerning serum cholesterol levels, suicidal behaviour and peripherical indices of serotoninergic function have been inconclusive for the moment. Investigations of the role of several intermediate clinical (depression, personality disorders, impulsivity) and biological (polyunsaturated fatty acids, serotonin) variables constitute current areas of active research.<p /> <p>Language: fr</p>
LA  - fr
SN  - 0003-4487
UR  - http://dx.doi.org/10.1016/j.amp.2005.07.012
ID  - ref1
ER  -