TY - JOUR PY - 2006// TI - Hypericum-induced mood disorder: Switch from depression to mixed episodes in two patients JO - International journal of psychiatry in clinical practice A1 - Raja, M. A1 - Azzoni, A. SP - 146 EP - 148 VL - 10 IS - 2 N2 - OBJECTIVE. To point out the danger of worsening mood disorders with the use of hypericum.

METHODS. Longitudinal clinical observation of two cases treated with hypericum.

RESULTS. The two patients underwent mixed episodes following hypericum treatment. One of them needed hospitalization for suicidal risk.

CONCLUSION. Caution is warranted in the use of hypericum in depressed patients with hidden bipolarity. Patients should be informed that hypericum may induce manic symptoms, increase cycling of mood states, or worsen the depressive state. © 2006 Taylor & Francis.

Language: en

LA - en SN - 1365-1501 UR - http://dx.doi.org/10.1080/13651500500305671 ID - ref1 ER -