TY - JOUR PY - 2010// TI - Poisoning by a forbidden "black stone" of paraphenylene-diamine: Systemic toxicity of PPD JO - Tijdschrift voor Geneeskunde A1 - Sinjan, E. A1 - Rutsaert, R. A1 - Druwe, P. SP - 826 EP - 829 VL - 66 IS - 17 N2 - For more than twenty years hair dye poisoning by intentional paraphenylene-diamine (PPD) ingestion has been a common and potentially severe way of suicide in Northern Africa, the Indian subcontinent and Saudi Arabia. We report the case of a 37-year-old Moroccan woman who committed suicide by deliberate ingestion of PPD. Systemic toxicity of PPD is characterized by acute respiratory distress secondary to laryngeal edema, rhabdomyolysis with myoglobinuria and a chocolate brown colored urine as well as acute renal failure. Myocardial injury may be a fatal complication. No specific antidote exists against PPD, the treatment remaining supportive. Mortality rate is high.

Language: nl

LA - nl SN - 0371-683X UR - http://dx.doi.org/10.2143/TVG.66.17.2000817 ID - ref1 ER -