TY  - JOUR
PY  - 2011//
TI  - Predictors of time to relapse/recurrence after electroconvulsive therapy in patients with major depressive disorder: A population-based cohort study
JO  - Depression research and treatment
A1  - Nordenskjöld, A.
A1  - von Knorring, L.
A1  - Engström, I.
SP  - 
EP  - 
VL  - 2011
IS  - 
N2  - OBJECTIVE. The aim of the study is to define predictors of relapse/recurrence after electroconvulsive therapy, ECT, for patients with major depressive disorder. <br><br>METHODS. A study of all patients (n=486) treated by means of ECT for major depressive disorder was performed. The data were derived from a regional quality register in Sweden. Psychiatric hospitalisation or suicide was used as a marker for relapse/recurrence. <br><br>RESULTS. The relapse/recurrence rate within one year after ECT was 34%. Factors associated with increased risk of relapse/recurrence included comorbid substance dependence and treatment with benzodiazepines or antipsychotics during the follow-up period. <br><br>CONCLUSIONS. Within the first years after ECT, relapses/recurrences leading to hospitalisation or suicide are common. Treatment with lithium might be beneficial, while benzodiazepines, antipsychotics, or continuation ECT does not seem to significantly reduce the risk of relapse/recurrence. © 2011 Axel Nordenskjöld et al.<p /> <p>Language: en</p>
LA  - en
SN  - 2090-1321
UR  - http://dx.doi.org/10.1155/2011/470985
ID  - ref1
ER  -