TY  - JOUR
PY  - 2014//
TI  - Epidemiology of organophosphate intoxication and predictors of intermediate syndrome
JO  - Turkish journal of medical sciences
A1  - Çolak, Ş.
A1  - Erdoǧan, M.Ö.
A1  - Baydin, A.
A1  - Afacan, M.A.
A1  - Katı, C.
A1  - Duran, L.
SP  - 279
EP  - 282
VL  - 44
IS  - 2
N2  - AIM: To evaluate the usefulness of plasma glucose and serum cholinesterase levels as predictors of organophosphate-induced intermediate syndrome. <br><br>MATERIALS AND METHODS: Seventy-one organophosphate poisoning patients who were admitted to our emergency department during a 4-year period were evaluated retrospectively. Four patients were excluded from the study due to a lack of medical records. Categorical variables were analyzed using the chi-square test and nonparametric variables were analyzed using the Mann-Whitney U test. <br><br>RESULTS: Thirty-five (52.2%) patients were male and 32(47.8%) were female. Patients had a mean age of 39.4 ± 15.9 years and 70.1% of the patients were married. Oral intake (68.7%) was the most common method of intoxication, and attempted suicide (67.2%) was the most common cause. Te most common organophosphates were methamidophos (20.8%), dichlorvos (19.4%), parathion (7.5%), and methyl parathion (7.5%). Fifty-seven (85%) patients were treated in the emergency observation unit and 10 (15%) patients were admitted to the intensive care unit. Eleven (16%) patients developed intermediate syndrome and had significantly lower levels of serum cholinesterase (P < 0.01) and higher blood glucose levels (P = 0.037). <br><br>CONCLUSION: Initial serum cholinesterase and glucose levels measured in the emergency department may be a useful marker in predicting organophosphate-induced intermediate syndrome. © TÜBİTAK.<p /> <p>Language: en</p>
LA  - en
SN  - 1300-0144
UR  - http://dx.doi.org/10.3906/sag-1211-31
ID  - ref1
ER  -