TY - JOUR PY - 2014// TI - Hyperprolactinemia with aripiprazole: Understanding the paradox JO - American journal of therapeutics A1 - Saraf, G. A1 - Behere, R.V. A1 - Venkatasubramanian, G. A1 - Rao, N.P. A1 - Varambally, S. A1 - Gangadhar, B.N. SP - e80 EP - e81 VL - 21 IS - 3 N2 - Aripiprazole, due to its partial agonist activity at the D2 receptors, is often recommended as the drug of choice in patients who develop antipsychotic-induced hyperprolactinemia. We report a case of a female patient who developed hyperprolactinemia while on treatment with aripiprazole. This partial D2 agonistic activity of aripiprazole could be dose related, and hence, at higher doses, aripiprazole by itself can have dopamine antagonistic properties and hence cause prolactin system abnormalities. © 2013 Lippincott Williams & Wilkins.
Language: en
LA - en SN - 1075-2765 UR - http://dx.doi.org/10.1097/MJT.0b013e3182456de7 ID - ref1 ER -