TY  - JOUR
PY  - 2015//
TI  - Life-threatening bradyarrhythmia with oral phenytoin overdose
JO  - Journal of pharmacology and pharmacotherapeutics
A1  - Srinivasan, G.
A1  - Wyawahare, M.
A1  - Mathen, P.G.
A1  - Subrahmanyam, D.K.
SP  - 179
EP  - 181
VL  - 6
IS  - 3
N2  - We report a case of a 41-year-old lady, who developed severe hypotension and sinus bradycardia, following oral consumption of 20 g of phenytoin and 500 mg of glibenclamide. She required high dose of inotropes and a temporary transvenous pacer for her hemodynamic instability. This life-threatening cardiotoxicity of phenytoin could have been due to its interaction with sulphonylurea. It is imperative to be aware of drug interactions, due to which, life-threatening cardiovascular manifestations following phenytoin toxicity can occur.<p /> <p>Language: en</p>
LA  - en
SN  - 0976-500X
UR  - http://dx.doi.org/10.4103/0976-500X.162017
ID  - ref1
ER  -