TY  - JOUR
PY  - 2016//
TI  - Autopsy results of a case of ingestion of sodium hydroxide solution
JO  - Journal of toxicologic pathology
A1  - Emoto, Y.
A1  - Yoshizawa, K.
A1  - Shikata, N.
A1  - Tsubura, A.
A1  - Nagasaki, Y.
SP  - 45
EP  - 47
VL  - 29
IS  - 1
N2  - Sodium hydroxide is a strongly corrosive alkali. We describe herein a case of suicide by ingestion of sodium hydroxide. A man in his 80s was found dead with a mug and a bottle of caustic soda. Macroscopically, liquefaction and/or disappearance of esophagus, trachea and lung tissue and a grayish discoloration of the mucosa of the stomach were seen along with blackish brown coloration of the skin, mouth, and oral cavity. The contents of the gastrointestinal tract showed a pH level of 7-8 on pH indicator strips. Histopathologically, liquefactive necrosis of remnant lung tissue and the stomach were seen. As biological reactions such as vasodilatation and inflammation were not detected in these organs, only a short number of hours must have passed between ingestion and death. This human case provides valuable information concerning the direct irritation induced by systemic exposure to corrosive substances. © 2016 The Japanese Society of Toxicologic Pathology.<p /> <p>Language: en</p>
LA  - en
SN  - 0914-9198
UR  - http://dx.doi.org/10.1293/tox.2015-0049
ID  - ref1
ER  -