TY  - JOUR
PY  - 2016//
TI  - Study of serum amylase and serum cholinesterase in organophosphorus poisoning
JO  - Journal of Krishna Institute of Medical Sciences University
A1  - Badiger, S.
A1  - Vishok, M.
SP  - 49
EP  - 56
VL  - 5
IS  - 2
N2  - BACKGROUND: Poisoning due to organophosphorus compounds is most commonly seen. Earlier plasma cholinesterase level was used to assess the severity of poisoning. Presently serum amylase is being recommended as a better indicator of severity. <br><br>AIMS AND OBJECTIVES: To study plasma cholinesterase and serum amylase levels in acute organophosphorus and to correlate serum amylase levels with clinical severity and outcome. Material and Methods: A total of 80 patients in the study admitted to a tertiary care centre within 24 hours with a history of organophosphorus poisoning were included in study. Estimation of plasma cholinesterase and serum amylase was done at the time of admission, and on 3rd day and on 5th day. <br><br>RESULTS: Occurrence of organophosphorus poisoning was more common among age group 21-30 years and among males (57.5%). They were 25 (31.2%) farmers, 23 (28.8%) students, and 22(27.5%) housewives. Monocrotophos (45.0%) was commonly used compound. Mean value of plasma cholinesterase and serum amylase at admission are 3693 U/L, and 185.4 U/L. There was significant inhibition of plasma cholinesterase and elevation of serum amylase at admission with return to normal values on 5th day. <br><br>CONCLUSION: Plasma cholinesterase inhibition <10% is associated with high degree of mortality. Hyperamylasemia >200 U/L has been associated with poor prognosis and proneness to respiratory failure. © Journal of Krishna Institute of Medical Sciences University.<p /> <p>Language: en</p>
LA  - en
SN  - 2231-4261
UR  - http://dx.doi.org/
ID  - ref1
ER  -