TY - JOUR PY - 2020// TI - Metformin-Induced Lactic Acidosis: A Question of Time JO - Case reports in critical care A1 - Bellefroid, C. A1 - Goffin, P. A1 - Guntz, J. A1 - Deville, M. SP - EP - VL - 2020 IS - N2 - Metformin is an oral antidiabetic largely prescribed in the treatment of type II diabetes. Overdose is associated with life-threatening lactic acidosis. We report the case of the highest metformin concentration ever described secondary to a voluntary suicidal intake. The patient developed a severe lactic acidosis and hemodynamic shock successfully treated with high-flow hemofiltration. Time to start extrarenal epuration is capital to avoid poor evolution. © 2020 Céline Bellefroid et al.

Language: en

LA - en SN - 2090-6420 UR - http://dx.doi.org/10.1155/2020/6962591 ID - ref1 ER -