TY - JOUR PY - 2021// TI - A practical utility and benefit of pharmacogenetic-based antidepressant treatment strategy for major depressive disorder patients with difficult-to-treat JO - Clinical psychopharmacology and neuroscience A1 - Lee, K.H. A1 - Bahk, W.-m. A1 - Lee, S.-j. A1 - Serretti, A. A1 - Pae, C.-u. SP - 160 EP - 165 VL - 19 IS - 1 N2 - OBJECTIVE: We report the results of pharmacogenomics-based antidepressant treatment (PGXt) results in treating treatment- resistant major depressive disorder (TRD) patients in real practice.

METHODS: Nine patients were prescribed Neuropharmagen? for selection of antidepressants for individual patient and their clinical outcomes were followed.

RESULTS: After treatment by PGXt results from current antidepressants, substantial reduction of depressive symptoms was observed at some point and maintained during observation period in six patients.

CONCLUSION: Our case series potentially shows the clinical utility and benefit of PGXt for treatment of TRD patients. © 2021 Korean College of Neuropsychopharmacology. All rights reserved.

Language: en

LA - en SN - 1738-1088 UR - http://dx.doi.org/10.9758/CPN.2021.19.1.160 ID - ref1 ER -