TY - JOUR PY - 2010// TI - El diagnóstico diferencial entre la Depresión Bipolar y la Depresión Monopolar en la práctica clínica JO - Revista Medica de Chile A1 - Leyton a, Fanny A1 - Barrera, Álvaro SP - 773 EP - 779 VL - 138 IS - 6 N2 - When assessing a patient with depression it is crucial not to miss a diagnosis of bipolar depression. In this review we suggest that it can be achieved, first, by consistently using standardised diagnostic criteria (e.g. DSM-IV-TR or ICD 10) and, second, by ascertaining the presence of some clinical features. The latter include previous episodes of mood elevation, current or past episodes of psychotic depression, onset of recurrent depressive disorder before the age of 25, a strong family history of mood disorder and suicide, lack of response or “wearing off” of response to well conducted antidepressant treatment, and an unusually fast response to antidepressants with features of elation. Although more and better research is required to establish the validity, sensitivity, specificity, and predictive value of each one of these features we suggest that from a practical point of view they would increase clinicians’ awareness of bipolar depression.

Language: es

LA - es SN - 0034-9887 UR - http://dx.doi.org/10.4067/S0034-98872010000600017 ID - ref1 ER -