TY - JOUR
PY - 2024//
TI - Anxiety and depression in people with post-COVID condition: a Belgian population-based cohort study three months after SARS-CoV-2 infection
JO - Social psychiatry and psychiatric epidemiology
A1 - D'Hondt, Stéphanie
A1 - Gisle, Lydia
A1 - de Pauw, Robby
A1 - Van Cauteren, Dieter
A1 - Demarest, Stefaan
A1 - Drieskens, Sabine
A1 - Cornelissen, Laura
A1 - De Ridder, Karin
A1 - Charafeddine, Rana
A1 - Smith, Pierre
SP - ePub
EP - ePub
VL - ePub
IS - ePub
N2 - PURPOSE: Since the onset of the COVID-19 pandemic, most research has focused on the management of the acute symptoms of the disease. Yet some people tend to experience symptoms beyond the acute phase, defined as Post-COVID-19 Condition (PCC). This study aims to assess the impact of COVID-19 and PCC on anxiety and depression.
METHODS: This is a prospective longitudinal cohort study among the Belgian adult population with recent SARS-CoV-2 infection for which contact tracing was initiated. A total of 3127 people were followed-up just after their infection and three months later (from April 2021 to January 2022). Anxiety and depression were assessed at the two stages using the GAD-7 (Generalized Anxiety Disorder) and the PHQ-9 (Patient Health Questionnaire).
RESULTS: Three months after infection, participants with PCC (50%) had an increased probability of having both anxiety and depressive symptoms (p < 0.001). The proportion with anxiety and depressive symptoms at three months were significantly higher in people with PCC (11% and 19%) compared to people without persistent COVID symptoms (3.8% and 4.2%) and to a matched sub-sample not infected with SARS-CoV-2 (6.5% and 4.3%). Having at least one acute COVID-19 symptom (p < 0.001), experiencing financial loss following the infection (p < 0.001), and different PCC symptoms were associated with anxiety and depressive symptoms worsening over time.
CONCLUSIONS: This study showed that three months after a SARS-CoV-2 infection, one in two people suffer from PCC with significant consequences for their mental health. Follow-up on mental health must therefore have an important place in people suffering from PCC.
Language: en
LA - en SN - 0933-7954 UR - http://dx.doi.org/10.1007/s00127-024-02655-9 ID - ref1 ER -