TY  - JOUR
PY  - 2022//
TI  - The clinical implication of psychiatric illnesses in patients with alcoholic liver disease: an analysis of US hospitals
JO  - Expert review of gastroenterology and hepatology
A1  - Urrunaga, Nathalie Helen
A1  - Blanchard, Jeremy
A1  - Lee, Ki Jung
A1  - Kwon, Jean
A1  - Chang, Kevin
A1  - Han, John
A1  - Fan, Gregory Hongyuan
A1  - Wang, Edwin
A1  - Chou, Harrison
A1  - Lee, David Uihwan
SP  - 689
EP  - 697
VL  - 16
IS  - 7
N2  - BACKGROUND: In this study, we evaluate the clinical impact of psychiatric illnesses (PI) on the hospital outcomes of patients admitted with alcoholic liver disease (ALD). <br><br>METHODS: From the National Inpatient Sample from 2012-2017, patients with alcoholic cirrhosis or alcoholic hepatitis were selected and stratified using the presence/absence of PI (which was a composite of psychiatric conditions). The cases were propensity score-matched to PI-absent controls and were compared to the following endpoints: mortality, death due to suicide, length of stay (LOS), hospitalization charges, and hepatic complications. <br><br>RESULTS: After matching, there were 122,907 PI with and 122,907 without PI. Those with PI were younger (51.8 vs. 51.9 years p = 0.02) and more likely to be female (39.2 vs. 38.7% p = 0.01); however, there was no difference in race. Patients with PI had lower rates of alcoholic cirrhosis but higher rates of alcoholic hepatitis/alcoholic hepatic steatosis. In multivariate, patients with PI had lower rates of all-cause mortality (aOR 0.51 95%CI 0.49-0.54); however, they experienced higher rates of deaths due to suicide (aOR 3.00 95%CI 1.56-5.78) and had longer LOS (aOR 1.02 95%CI 1.01-1.02). <br><br>CONCLUSION: Presence of PI in ALD patients is associated with prolonged hospital stay and higher rates deaths due to suicide.<p /> <p>Language: en</p>
LA  - en
SN  - 1747-4124
UR  - http://dx.doi.org/10.1080/17474124.2022.2090337
ID  - ref1
ER  -