TY  - JOUR
PY  - 2020//
TI  - Neurological Changes and Depression: 2020 Update
JO  - Clinics in geriatric medicine
A1  - Greene, Ryan D.
A1  - Cook, Alex
A1  - Nowaskie, Dustin
A1  - Wang, Sophia
SP  - 297
EP  - 313
VL  - 36
IS  - 2
N2  - This article covers current research on the relationship between depression and cognitive impairment in older adults. First, it approaches the clinical assessment of late-life depression and comorbid cognitive impairment. Cognitive risk factors for suicide are discussed. Research is then provided on neuropsychological changes associated with depression, discussing subjective cognitive impairment, mild cognitive impairment, and dementia profiles. In addition, literature regarding neuroimaging and biomarker findings in depressed older adults is presented. Finally, therapeutic models for treatment of late-life depression are discussed, including psychotherapy models, holistic treatments, pharmacologic approaches, and brain stimulation therapies.<p /> <p>Language: en</p>
LA  - en
SN  - 0749-0690
UR  - http://dx.doi.org/10.1016/j.cger.2019.11.009
ID  - ref1
ER  -