TY  - JOUR
PY  - 2021//
TI  - Effectiveness of collaborative care in reducing suicidal ideation: An individual participant data meta-analysis
JO  - General hospital psychiatry
A1  - Grigoroglou, Christos
A1  - van der Feltz-Cornelis, Christina
A1  - Hodkinson, Alexander
A1  - Coventry, Peter A.
A1  - Zghebi, Salwa S.
A1  - Kontopantelis, Evangelos
A1  - Bower, Peter
A1  - Lovell, Karina
A1  - Gilbody, Simon
A1  - Waheed, Waquas
A1  - Dickens, Christopher
A1  - Archer, Janine
A1  - Blakemore, Amy
A1  - Adler, David A.
A1  - Aragonès, Enric
A1  - Björkelund, Cecilia
A1  - Bruce, Martha L.
A1  - Buszewicz, Marta
A1  - Carney, Robert M.
A1  - Cole, Martin G.
A1  - Davidson, Karina W.
A1  - Gensichen, Jochen
A1  - Grote, Nancy K.
A1  - Russo, Joan
A1  - Huijbregts, Klaas
A1  - Huffman, Jeff C.
A1  - Menchetti, Marco
A1  - Patel, Vikram
A1  - Richards, David A.
A1  - Rollman, Bruce
A1  - Smit, Annet
A1  - Zijlstra-Vlasveld, Moniek C.
A1  - Wells, Kenneth B.
A1  - Zimmermann, Thomas
A1  - Unützer, Jurgen
A1  - Panagioti, Maria
SP  - 27
EP  - 35
VL  - 71
IS  - 
N2  - To assess whether CC is more effective at reducing suicidal ideation in people with depression compared with usual care, and whether study and patient factors moderate treatment effects.  METHOD: We searched Medline, Embase, PubMed, PsycINFO, CINAHL, CENTRAL from inception to March 2020 for Randomised Controlled Trials (RCTs) that compared the effectiveness of CC with usual care in depressed adults, and reported changes in suicidal ideation at 4 to 6 months post-randomisation. Mixed-effects models accounted for clustering of participants within trials and heterogeneity across trials. This study is registered with PROSPERO, CRD42020201747.  RESULTS: We extracted data from 28 RCTs (11,165 patients) of 83 eligible studies. We observed a small significant clinical improvement of CC on suicidal ideation, compared with usual care (SMD, -0.11 [95%CI, -0.15 to -0.08]; I2, 0·47% [95%CI 0.04% to 4.90%]). CC interventions with a recognised psychological treatment were associated with small reductions in suicidal ideation (SMD, -0.15 [95%CI -0.19 to -0.11]). CC was more effective for reducing suicidal ideation among patients aged over 65 years (SMD, - 0.18 [95%CI -0.25 to -0.11]).  CONCLUSION: Primary care based CC with an embedded psychological intervention is the most effective CC framework for reducing suicidal ideation and older patients may benefit the most.<p /> <p>Language: en</p>
LA  - en
SN  - 0163-8343
UR  - http://dx.doi.org/10.1016/j.genhosppsych.2021.04.004
ID  - ref1
ER  -