TY  - JOUR
PY  - 2020//
TI  - Circadian rhythm in negative affect: Implications for mood disorders
JO  - Psychiatry research
A1  - Emens, Jonathan S.
A1  - Berman, Alec M.
A1  - Thosar, Saurabh S.
A1  - Butler, Matthew P.
A1  - Roberts, Sally A.
A1  - Clemons, Noal A.
A1  - Herzig, Maya X.
A1  - McHill, Andrew W.
A1  - Morimoto, Miki
A1  - Bowles, Nicole P.
A1  - Shea, Steven A.
SP  - e113337
EP  - e113337
VL  - 293
IS  - 
N2  - In humans, there is an endogenous, near 24-h (i.e., circadian) variation in mood with the best mood occurring during the circadian day and the worst mood occurring during the circadian night. Only positive affect, and not negative affect, has been shown to contribute to this circadian rhythm. We discovered a sharp circadian peak in negative affect during the circadian night coincident with a circadian trough in positive affect. These findings may help explain the association of depression with insomnia, the increased risk of suicide with nocturnal wakefulness, and the correlation between circadian misalignment and symptom severity in Major Depressive Disorder.<p /> <p>Language: en</p>
LA  - en
SN  - 0165-1781
UR  - http://dx.doi.org/10.1016/j.psychres.2020.113337
ID  - ref1
ER  -