TY  - JOUR
PY  - 1992//
TI  - Mechanisms and stereochemistry of the activation of (2S)- and (2R)-serine O-sulfate as suicide inhibitors for Escherichia coli glutamic acid decarboxylase
JO  - Journal of the Chemical Society, Chemical Communications
A1  - Rose, J.E.
A1  - Leeson, P.D.
A1  - Gani, D.
SP  - 1784
EP  - 1786
VL  - 
IS  - 24
N2  - E. coli glutamic acid decarboxylase is inactivated by both enantiomers of the suicide inhibitor serine O-sulfate, inactivation by the (2S)-enantiomer involving Cα-H bond cleavage and inactivation by the (2R)-isomer involving Cα-decarboxylation; both processes occur on the 4′-Re-face of the coenzyme, the opposite face to that utilised in the physiological decarboxylation reaction.<p /> <p>Language: en</p>
LA  - en
SN  - 0022-4936
UR  - http://dx.doi.org/10.1039/C39920001784
ID  - ref1
ER  -