TY  - JOUR
PY  - 1996//
TI  - Is there a peripheral marker of suicidality? A pilot study of auto-aggressive males
JO  - Journal of Serotonin Research
A1  - Keeley, H.
A1  - Nolan, M.
A1  - Hooley, K.
A1  - Morgan, E.
A1  - Kelleher, M.J.
SP  - 35
EP  - 42
VL  - 3
IS  - 1
N2  - Abnormal serotonin function has been implicated in suicidality through the concept of impulsive aggression. Platelet serotonin aggregation is a possible valid peripheral marker of central serotonin function. A group of male prisoners considered at risk of suicide and hence under special observations, is compared with a control male group. None of the subjects was taking anti-depressant medications. A marked reduction in serotonin aggregation is noted in those with a history of auto-aggressive acts compared both with controls and with those tests who do not have such a history. The implications and drawbacks of the study are discussed with regard to the possibility of identifying a specific biological marker for a pre-disposition towards suicide.<p /> <p>Language: en</p>
LA  - en
SN  - 1350-7702
UR  - http://dx.doi.org/
ID  - ref1
ER  -