TY  - JOUR
PY  - 1992//
TI  - Determination of zopiclone in plasma using column liquid chromatography with ultraviolet detection
JO  - Journal of chromatography
A1  - Royer-Morrot, M. J.
A1  - Rambourg, M.
A1  - Jacob, I.
A1  - Bauer, P.
A1  - Royer, R. J.
SP  - 297
EP  - 299
VL  - 581
IS  - 2
N2  - A reversed-phase liquid chromatographic method with ultraviolet detection for the determination of zopiclone in plasma is described. It is rapid, sensitive, reproducible and linear over a wide range. The method was used to study plasma zopiclone concentrations in a case of acute intoxication after oral ingestion of 300 mg of the drug. The plasma level was 1600 ng/ml 4.5 h after the dose and the elimination half-life was 3.5 h.<p /> <p>Language: en</p>
LA  - en
SN  - 
UR  - http://dx.doi.org/10.1016/0378-4347(92)80286-y
ID  - ref1
ER  -