TY  - JOUR
PY  - 1994//
TI  - Thioridazine enantiomers in human tissues
JO  - Forensic science international
A1  - Jortani, S. A.
A1  - Valentour, J. C.
A1  - Poklis, A.
SP  - 165
EP  - 170
VL  - 64
IS  - 2-3
N2  - Enantiomers of thioridazine (TRZ) were determined in postmortem tissues obtained from a patient on chronic TRZ therapy by sequential achiral and chiral high pressure liquid chromatography. Tissue concentrations of (+)-TRZ found in liver, brain, bile and blood were: 6.46, 0.40, 0.48 and 0.07 mg/l or mg/kg, respectively. Concentrations of (-)-TRZ in liver, brain, bile and blood were: 12.2, 0.81, 1.07 and 0.20 mg/l or mg/kg, respectively. These data demonstrate the stereoselective disposition of TRZ in human tissues.<p /> <p>Language: en</p>
LA  - en
SN  - 0379-0738
UR  - http://dx.doi.org/10.1016/0379-0738(94)90227-5
ID  - ref1
ER  -