TY  - JOUR
PY  - 1994//
TI  - Folinic acid and enhanced renal elimination in formic acid intoxication
JO  - Journal of toxicology - clinical toxicology
A1  - Moore, D. F.
A1  - Bentley, A. M.
A1  - Dawling, S.
A1  - Hoare, A. M.
A1  - Henry, J. A.
SP  - 199
EP  - 204
VL  - 32
IS  - 2
N2  - Ingestion of over 60 g of formic acid by an adult is potentially fatal. We report a case of a 36-year-old woman with a history of depression who ingested 110 g of formic acid. She survived a complicated intensive care hospitalization following usage of intravenous folinic acid, urinary alkalinization, intravenous furosemide and supportive care. We suggest a management protocol aimed at minimizing formate toxicity by enhancing hepatic formate degradation via the folinic acid 'one carbon pool' and by enhanced renal elimination of formate.<p /> <p>Language: en</p>
LA  - en
SN  - 0731-3810
UR  - http://dx.doi.org/10.3109/15563659409000451
ID  - ref1
ER  -