TY  - JOUR
PY  - 1995//
TI  - Case report: reversible QT prolongation with torsades de pointes in a patient with pimozide intoxication
JO  - American journal of the medical sciences
A1  - Krähenbühl, S.
A1  - Sauter, B.
A1  - Kupferschmidt, H.
A1  - Krause, M.
A1  - Wyss, P. A.
A1  - Meier, P. J.
SP  - 315
EP  - 316
VL  - 309
IS  - 6
N2  - Pimozide is a diphenylpiperidine neuroleptic with well characterized cardiovascular side effects including QT prolongation. So far, life-threatening cardiac arrhythmias, in particular torsades de pointes, have not been described in patients treated with pimozide. The authors describe a patient in whom torsades de pointes developed after the ingestion of 800 mg pimozide as a suicide attempt. After intravenous treatment with lidocaine and magnesium, the patient recovered completely and the QT interval had normalized 5 days after the intoxication. Potential mechanisms leading to torsades de pointes in patients treated with pimozide are discussed.<p /> <p>Language: en</p>
LA  - en
SN  - 0002-9629
UR  - http://dx.doi.org/10.1097/00000441-199506000-00003
ID  - ref1
ER  -