TY - JOUR PY - 1991// TI - Fluoroacetate and fluorocitrate: mechanism of action JO - Neurochemical research A1 - Clarke, D. D. SP - 1055 EP - 1058 VL - 16 IS - 9 N2 - The concept of lethal synthesis as suggested by Peters is reviewed in the light of the more recent work in this area. It is suggested that fluorocitrate is a "suicide" substrate for aconitase rather than a competitive inhibitor as originally suggested. The use of these substances to study glial-neuronal relationships is considered.

Language: en

LA - en SN - 0364-3190 UR - http://dx.doi.org/10.1007/BF00965850 ID - ref1 ER -