TY - JOUR PY - 1998// TI - [Digitalis poisoning treated with a specific antidote] JO - Tidsskrift for den Norske Laegeforening A1 - Rykke, E. O. A1 - Bredesen, J. E. A1 - Stokland, O. A1 - Jacobsen, D. SP - 408 EP - 410 VL - 118 IS - 3 N2 - Toxicity by digitalis is a common problem in everyday clinical practice. In this paper three cases of severe poisoning with digitoxin with maximal S-digitoxin levels of 115, 150 and 239 nmol/l are described. All patients received specific digoxin Fab-fragment intravenously. Administration of antidotes resulted in a favourable outcome in all three patients. So far, the use of digoxin-specific antibodies has been limited to a few cases of severe intoxication where life-threatening arrhythmias and hyperkalaemia were present. We discuss whether a more liberal indication should be accepted.

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LA - no SN - 0029-2001 UR - http://dx.doi.org/ ID - ref1 ER -