TY  - JOUR
PY  - 2001//
TI  - Depression does not influence basal ganglia-mediated psychomotor speed in HIV-1 infection
JO  - Journal of neuropsychiatry and clinical neurosciences
A1  - von Giesen, H. J.
A1  - Backer, R.
A1  - Hefter, H.
A1  - Arendt, G.
SP  - 88
EP  - 94
VL  - 13
IS  - 1
N2  - The authors examined the effects of depressive mood (Hamilton Rating Scale for Depression [Ham-D]) on basal ganglia-mediated psychomotor speed (motor test battery) in 202 HIV-1 seropositive homosexual males with no prior history of antiretroviral treatment. HIV-1 seropositive patients showed a significant slowing of most rapid alternating movements (MRAM) and significantly prolonged contraction times (CT) compared with 66 HIV-1 seronegative male control subjects. Factor analysis of Ham-D scores isolated a factor containing the items depressed mood, suicide, and psychic and somatic anxiety. This factor did not correlate with MRAM or CT. Depression and psychomotor speed are independent in HIV-1infection.<p /> <p>Language: en</p>
LA  - en
SN  - 0895-0172
UR  - http://dx.doi.org/10.1176/jnp.13.1.88
ID  - ref1
ER  -