TY - JOUR PY - 2001// TI - Death following cupric sulfate emesis JO - Journal of toxicology - clinical toxicology A1 - Liu, J. A1 - Kashimura, S. A1 - Hara, K. A1 - Zhang, G. SP - 161 EP - 163 VL - 39 IS - 2 N2 - A 25-year-old woman who had ingested about 20 tablets of diazepam 2.5 mg in a suicide attempt was given cupric sulfate 2.5 g in 1750 mL water as an emetic, but died 3 days later. On autopsy, death was attributed to acute hemolysis and acute renal failure due to copper poisoning. Copper concentrations were 5.31 microg/mL in whole blood, 19.0 microg/g in the liver, 8.9 microg/g in the kidney, 1.1 microg/L in the brain, 1.1 microg/g in the gastric wall, 1.5 microg/g in the jejunal wall, 0.3 microg/g in the colon wall, 4.6 microg/g in the gastric contents, and 12.6 microg/g in the intestinal contents (fresh weight). This case and 10 others from the Chinese medical literature provide additional evidence that cupric sulfate is a corrosive poison and contraindicated as an emetic.

Language: en

LA - en SN - 0731-3810 UR - http://dx.doi.org/10.1081/clt-100103832 ID - ref1 ER -