TY - JOUR PY - 2001// TI - Clinical correlates of psychiatric comorbidity in bipolar I patients JO - Bipolar disorders A1 - Vieta, E. A1 - Colom, F. A1 - Corbella, B. A1 - Martínez-Arán, A. A1 - Reinares, M. A1 - Benabarre, A. A1 - Gastó, C. SP - 253 EP - 258 VL - 3 IS - 5 N2 - OBJECTIVES: To ascertain the clinical implications of psychiatric comorbidity in the course and outcome of bipolar I patients. METHODS: One hundred and twenty-nine bipolar I outpatients in remission [Young Mania Rating Scale (Y-MRS) < 7, Hamilton Depression Rating Scale (HDRS) < 9] were assessed by means of the Structured Clinical Interview for DSM-III-R axis I and axis II (SCID-I and SCID-II) in order to detect all possible psychiatric comorbid diagnoses. The sample was split according to the presence of psychiatric comorbidity and the groups were compared. RESULTS: Psychiatric comorbidity was detected in 31% of the sample. A higher number of mixed features, depressive episodes and suicide attempts and a predominance of depressive onset amongst comorbid bipolar patients were the most relevant differences between the two groups. CONCLUSIONS: There is an association between depression, suicidality and comorbidity in bipolar I disorder. As comorbidity had a clear relevance in the course and outcome of bipolar illness, this issue should be specifically assessed in clinical practice.
Language: en
LA - en SN - 1398-5647 UR - http://dx.doi.org/ ID - ref1 ER -