TY - JOUR PY - 2000// TI - [Event-related potentials and suicide behavior in patients with affective disorder] JO - Zhonghua Yi Xue Za Zhi (Beijing) A1 - Wang, J. A1 - Chen, X. A1 - Lou, F. SP - 275 EP - 277 VL - 80 IS - 4 N2 - OBJECTIVE: To investigate P300 and contingent negative variations (CNV) of patients with affective disorder and its clinical significance. METHODS: 39 depressives, 22 maniacs and 33 normal controls were included in this study. Both P300 and CNV were recorded in every subject, using a nicolet spirit instrument. RESULTS: Both depression and mania groups presented prolonged P300-P3b latency and decreased P300-P3 and CNV amplitudes compared with normal controls. Decreased P300 & CNV amplitudes were further related to the history of suicide behavior in the two patient groups. CONCLUSION: The clinical significance of event-related potentials was confirmed in this study, while the biological correlates of suicide behavior need further and intensive study.
Language: zh
LA - zh SN - 0376-2491 UR - http://dx.doi.org/ ID - ref1 ER -