TY  - JOUR
PY  - 2003//
TI  - Comorbid personality disorder predicts suicide after major depression: a 10-year follow-up
JO  - Acta psychiatrica Scandinavica
A1  - Hansen, P. E. B.
A1  - Wang, A. G.
A1  - Stage, K. B.
A1  - Kragh-Sorensen, P.
A1  - Danish University Antidepressant Group, 
SP  - 436
EP  - 440
VL  - 107
IS  - 6
N2  - OBJECTIVE: To identify psychopathological predictors for suicide in a population of major depressed Diagnostic Statistical Manual-III (DSM-III) in-patients.  METHOD: A total of 210 previous participants in multicentre antidepressant drug trials, carried out in a randomized double-blind design, were followed prospectively through a maximum of 10 years. Patients with a drug or alcohol abuse were excluded. The association between suicide and the pretreatment psychopathological profile was analysed using survival statistics.  RESULTS: The suicide rate for non-melancholic depressed patients was significantly higher than for melancholic depressed patients. Comorbid personality disorder was independently associated with an increased suicide rate [relative hazard 3.41(CI: 1.15-10.10)].  CONCLUSION: The study indicates that the non-melancholic aspect of depression, and especially comorbid personality disorder, is associated with an increased suicidal vulnerability.<p /> <p>Language: en</p>
LA  - en
SN  - 0001-690X
UR  - http://dx.doi.org/
ID  - ref1
ER  -