TY  - JOUR
PY  - 2002//
TI  - Sensory evoked potentials in patients with affective disorders accompanying suicidal behavior
JO  - Chinese medical journal
A1  - Wang, Hongxing
A1  - Chen, Xingshi
A1  - Bai, Peishen
A1  - Yin, Ling
SP  - 1675
EP  - 1678
VL  - 115
IS  - 11
N2  - OBJECTIVE: To investigate the variations of sensory evoked potentials (SEPs) in patients with affective disorders accompanying suicidal behavior.  METHODS: 39 depressive patients, 22 manic patients and 33 normal controls were included in the study. Visual, auditory and somatosensory evoked potentials (VEP, AEP & SSEP) were recorded from every subject using a Nicolet Spirit Instrument.  RESULTS: Both the depressive and manic groups presented prolonged latencies and decreased amplitudes of major components of SEPs as compared to that of normal controls. Depressive patients with suicidal behavior had decreased P(3) amplitude of VEP (P < 0.05), while maniacs with suicidal behavior had decreased P(2) amplitudes of VEP & AEP (P < 0.05 or 0.01). Compared with patients without suicidal behavior, patients with suicidal behavior had significantly decreased P(3) amplitudes of VEP & SSEP.  CONCLUSIONS: The variations of SEPs in patients with affective disorders is closely associated with a history of suicidal behavior. Their clinical significance and biological correlates with suicidal behavior need further study.<p /> <p>Language: en</p>
LA  - en
SN  - 0366-6999
UR  - http://dx.doi.org/
ID  - ref1
ER  -