TY  - JOUR
PY  - 2005//
TI  - Mother and fetus both survive from severe paraquat intoxication
JO  - Clinical toxicology (Philadelphia, Pa.)
A1  - Jenq, Chang-Chyi
A1  - Wu, Chien-Der
A1  - Lin, Ja-Liang
SP  - 291
EP  - 295
VL  - 43
IS  - 4
N2  - Paraquat, 1,1'-dimethyl-4,4'-bipyridylium dichloride, is a commonly applied bipyridyl contact herbicide. Paraquat poisoning from suicidal ingestion causes high mortality rates, and severe poisoning has been uniformly fatal in pregnant females (nine of nine cases). We presented a case of severe paraquat poisoning from suicidal ingestion in a woman in the third trimester of pregnancy (G5P4A1). Urine dithionate test was strongly positive (showed dark blue color). She was managed with charcoal hemoperfusion x 2, megadose of cyclophosphamide, and methylprednisolone pulse therapy. Despite initial deterioration of renal and liver function, she had a normal spontaneous delivery of a healthy girl baby 14 weeks after the exposure. The child reached developmental milestones normally and appeared healthy and well nourished at age 5. This may be the first documentation of a pregnant woman with moderate to severe paraquat poisoning successfully delivering a healthy baby.<p /> <p>Language: en</p>
LA  - en
SN  - 1556-3650
UR  - http://dx.doi.org/
ID  - ref1
ER  -