TY  - JOUR
PY  - 2007//
TI  - Severe lactic acidosis and rhabdomyolysis following metformin and ramipril overdose
JO  - British journal of anaesthesia
A1  - Galea, M.
A1  - Jelacin, N.
A1  - Bramham, K.
A1  - White, I.
SP  - 213
EP  - 215
VL  - 98
IS  - 2
N2  - We report the case of a 46-yr-old male who developed severe lactic acidosis, cardiorespiratory arrest, and rhabdomyolysis following an overdose of metformin and ramipril. The lactic acidosis was successfully treated with early high-volume continuous veno-venous haemofiltration. Rhabdomyolysis and lower limb compartment syndrome developed later. The patient otherwise made a good recovery. We discuss the management of severe lactic acidosis secondary to metformin overdose and the association with rhabdomyolysis.<p /> <p>Language: en</p>
LA  - en
SN  - 0007-0912
UR  - http://dx.doi.org/10.1093/bja/ael347
ID  - ref1
ER  -