TY  - JOUR
PY  - 2010//
TI  - Comorbidities of obsessive and compulsive symptoms in Huntington's disease
JO  - Journal of nervous and mental disease
A1  - Anderson, Karen E.
A1  - Gehl, Carissa R.
A1  - Marder, Karen S.
A1  - Beglinger, Leigh J.
A1  - Paulsen, Jane S.
A1  - Huntington's Study Group, 
SP  - 334
EP  - 338
VL  - 198
IS  - 5
N2  - Although current reports document a high rate of obsessive and compulsive symptoms (O/Cs) in Huntington's disease (HD), there have been no studies published that have made an attempt to identify comorbidities of O/Cs in HD. We examined O/Cs in 1642 individuals with a diagnosis of HD. Of those endorsing significant O/Cs (27.2%), nearly one-quarter reported obtaining treatment for obsessive compulsive disorder. Individuals with HD and O/Cs were older, had poorer functioning, and a longer duration of illness than those without O/Cs. Individuals with HD and O/Cs endorsed significantly higher psychiatric comorbidities of depression, suicidal ideation, aggression, delusions, and hallucinations. Participants with the most severe O/Cs and worse performance on the Stroop task, a measure of executive function. Clinicians should be aware that patients with HD and O/Cs might have a somewhat different clinical picture from those without, and may require a specialized treatment plan.<p /> <p>Language: en</p>
LA  - en
SN  - 0022-3018
UR  - http://dx.doi.org/10.1097/NMD.0b013e3181da852a
ID  - ref1
ER  -