TY  - JOUR
PY  - 2009//
TI  - Suicidal Isoniazid poisoning
JO  - Journal of Ayub Medical College
A1  - Khoharo, Haji Khan
A1  - Ansari, Shuaib
A1  - Abro, Allauddin
A1  - Qureshi, Fatima
SP  - 178
EP  - 179
VL  - 21
IS  - 2
N2  - Accidental or intentional Isoniazid poisoning may manifest within half to three hours as intractable seizure, acidosis, and coma. Single high dose of pyridoxine was used as an antidote with good response as reported earlier. Ingestion of more than 80 mg/kg body weight produces severe central nervous system symptoms and a dose of 125 mg/kg is potentially lethal if not promptly treated. We report a case of suicidal attempt with use of Isoniazid, who developed grand mal seizures and was controlled with diazepam and symptomatic treatment.<p /> <p>Language: en</p>
LA  - en
SN  - 1025-9589
UR  - http://dx.doi.org/
ID  - ref1
ER  -