TY  - JOUR
PY  - 2010//
TI  - The strong relationship between bipolar and substance-use disorder
JO  - Annals of the New York Academy of Sciences
A1  - Swann, Alan C.
SP  - 276
EP  - 293
VL  - 1187
IS  - 
N2  - Bipolar disorder and substance-use disorders commonly occur in the same individual. In fact, bipolar disorder has a higher prevalence of substance-use disorders than any other psychiatric illness. Individuals with both disorders have a more severe course of bipolar disorder, including earlier onset, more frequent episodes, and more complications, including anxiety- and stress-related disorders, aggressive behavior, legal problems, and suicide. Bipolar and substance-use disorders share common mechanisms, including impulsivity, poor modulation of motivation and responses to rewarding stimuli, and susceptibility to behavioral sensitization. Studies of potential treatments for bipolar substance-use disorder have paid scant attention to the combined disorders. The most promising treatment strategies are those that address their shared mechanisms.<p /> <p>Language: en</p>
LA  - en
SN  - 0077-8923
UR  - http://dx.doi.org/10.1111/j.1749-6632.2009.05146.x
ID  - ref1
ER  -