TY - JOUR PY - 2011// TI - Successful treatment of methemoglobinemia and acute renal failure after indoxacarb poisoning JO - Clinical toxicology (Philadelphia, Pa.) A1 - Park, Jung Soo A1 - Kim, Hoon A1 - Lee, Suk Woo A1 - Min, Jin Hong SP - 744 EP - 746 VL - 49 IS - 8 N2 - CONTEXT: We report a case of systemic toxicity induced by indoxacarb, an oxadiazine insecticide. Previous reports have suggested the occurrence of methemoglobinemia after indoxacarb ingestion, but no case of indoxacarb-induced systemic toxicity, such as acute renal failure, has been reported thus far. CASE DETAILS: A 71-year-old woman presented with indoxacarb poisoning, resulting in methemoglobinemia and acute renal failure. The methemoglobinemia improved after methylene blue administration, but rapidly progressive acute renal failure occurred 7 h after admission. She was treated with continuous veno-venous hemofiltration and intravenous sodium bicarbonate and recovered successfully. DISCUSSION: Ingestion of indoxacarb may produce not only methemoglobinemia, but also systemic toxicities like acute renal failure, which can be successfully treated with aggressive therapy such as continuous veno-venous hemofiltration. Physicians should be alert to acute renal failure as a possible complication of indoxacarb ingestion, and treat it accordingly.
Language: en
LA - en SN - 1556-3650 UR - http://dx.doi.org/10.3109/15563650.2011.602080 ID - ref1 ER -